ABSTRACT Objective: The aim of this study was to investigate the effect adding visceral manipulation to exercise program on pain, range of motion, function, and scapular protraction in patients with non-specific neck dysfunction (NSND) after dyspepsia.Design: A single-blinded, randomized controlled study. Setting: Outpatient physical therapy setting.Methods: Sixty patients with NSND after dyspepsia (18-43 years) were recruited and allocated randomly into 3 equal groups.Intervention: Visceral Manipulation (VM) group, exercises group (EX) and VM plus EX group. The program was carried out 3 times a week for 6 weeks.Outcome measures: The cervical range of motion device for neck range of motion, Tape Measure for scapular protraction, Neck Disability Index (NDI) for neck function and visual analog scale for pain were used to assess participants at baseline and after 6 weeks of treatment. Results: There were statistically significant differences between the three groups on neck range of motion, neck pain, Cranio-cervical flexion, functional activity, and scapular retraction with preferring to VM plus Ex-group (p < 0.05). After six weeks of treatment, the mean (SD) for Pain and NDI were 18.75±6.85mm and 15.96±4.13 in the combined group; 227±8.01mm and 10.95±2.44 in the Ex-group; 37.75±8.65mm and 28.05±5.4 in the VM-group respectively.Conclusion: Adding VM to exercises was superior to either VM or exercises alone in improving range of motion, pain, functional activity, and shoulder retraction in patients with NSND after dyspepsia. However, exercises were more effective than VM on neck range of motion, craniocervical flexion, neck pain, functional activity, and scapular protraction.