E-ISSN 2577-5669
 

Original Research 


Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities

Ishaku L. Elisha*, Jurbe G. Gotep, Micah S. Makoshi, Joy G. Usman, Blessing Z. Shok, Kehinde F. Oyebade, Zainab Muhammad, Itodo E. Akogwu, Kpensalen B. Tondo, Hong Joseph, Edirin J. Akpojosevbe, Bitrus Yakubu, Maryam Muhammad Drug Development Division, National Veterinary Research Institute P.M.B. 01 Vom, Plateau Stat.

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  • Abstract
    Euphorbia hirta L.. is a common herb with global spread. Different parts of E. hirta are used in traditional medicine for the treatment of a variety of human and animal conditions, such as skin diseases, inflammation, digestive and respiratory disorders. This bibliometric study aimed to provide a panoramic view of the publication landscape in the last thirty years of Euphorbia hirta research. VOSviewer was used to analyze 603 documents retrieved from Scopus database during the period, 1992 to 2021. Dominant research themes in the last thirty years were centred on the application of crude extracts or isolated compounds from E. hirta against diabetes, oxidative stress, inflammation, tuberculosis, snake bite, gastro-intestinal disorders, respiratory infections, skin pathologies, bacterial, fungal and viral infections. Current paradigm shift in E. hirta research are targeted at improving the efficacy of phytomolecules against resistant bacterial pathogens and cancer cells via green synthesis of nanoparticles and the application of in silico technologies in predicting the activities of nano-phytomolecules against SARS-CoV-2 and the dengue virus. This study recommends further research in the determination of the bioavailability of molecules in in vivo models. Researchers should carry out more preclinical investigations with the aim of establishing the pharmacokinetic and pharmacodynamic properties of phytocompounds instead of relying solely on in silico predictions.

    Key words: Bibliometrics, biological activities, Euphorbia hirta, specialised metabolites, trends


     
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     Articles by Ishaku L. Elisha*
    Articles by Jurbe G. Gotep
    Articles by Micah S. Makoshi
    Articles by Joy G. Usman
    Articles by Blessing Z. Shok
    Articles by Kehinde F. Oyebade
    Articles by Zainab Muhammad
    Articles by Itodo E. Akogwu
    Articles by Kpensalen B. Tondo
    Articles by Hong Joseph
    Articles by Edirin J. Akpojosevbe
    Articles by Bitrus Yakubu
    Articles by Maryam Muhammad Drug Development Division
    Articles by National Veterinary Research Institute P.M.B. 01 Vom
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    How to Cite this Article
    Pubmed Style

    Elisha IL, Gotep JG, Makoshi MS, Usman JG, Shok BZ, KFO, Muhammad Z, Akogwu IE, Tondo KB, Joseph H, Akpojosevbe EJ, Yakubu B, Division MMDD, , Stat P. Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities. J Complement Med Res. 2023; 14(1): 81-92. doi:10.5455/jcmr.2023.14.01.16


    Web Style

    Elisha IL, Gotep JG, Makoshi MS, Usman JG, Shok BZ, KFO, Muhammad Z, Akogwu IE, Tondo KB, Joseph H, Akpojosevbe EJ, Yakubu B, Division MMDD, , Stat P. Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities. https://www.jocmr.com/?mno=29106 [Access: May 26, 2023]. doi:10.5455/jcmr.2023.14.01.16


    AMA (American Medical Association) Style

    Elisha IL, Gotep JG, Makoshi MS, Usman JG, Shok BZ, KFO, Muhammad Z, Akogwu IE, Tondo KB, Joseph H, Akpojosevbe EJ, Yakubu B, Division MMDD, , Stat P. Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities. J Complement Med Res. 2023; 14(1): 81-92. doi:10.5455/jcmr.2023.14.01.16



    Vancouver/ICMJE Style

    Elisha IL, Gotep JG, Makoshi MS, Usman JG, Shok BZ, KFO, Muhammad Z, Akogwu IE, Tondo KB, Joseph H, Akpojosevbe EJ, Yakubu B, Division MMDD, , Stat P. Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities. J Complement Med Res. (2023), [cited May 26, 2023]; 14(1): 81-92. doi:10.5455/jcmr.2023.14.01.16



    Harvard Style

    Elisha, I. L., Gotep, . J. G., Makoshi, . M. S., Usman, . J. G., Shok, . B. Z., , . K. F. O., Muhammad, . Z., Akogwu, . I. E., Tondo, . K. B., Joseph, . H., Akpojosevbe, . E. J., Yakubu, . B., Division, . M. M. D. D., & Stat, . P. (2023) Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities. J Complement Med Res, 14 (1), 81-92. doi:10.5455/jcmr.2023.14.01.16



    Turabian Style

    Elisha, Ishaku L., Jurbe G. Gotep, Micah S. Makoshi, Joy G. Usman, Blessing Z. Shok, Kehinde F. Oyebade, Zainab Muhammad, Itodo E. Akogwu, Kpensalen B. Tondo, Hong Joseph, Edirin J. Akpojosevbe, Bitrus Yakubu, Maryam Muhammad Drug Development Division, National Veterinary Research Institute P.M.B. Vom, and Plateau Stat. 2023. Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities. Journal of Complementary Medicine Research, 14 (1), 81-92. doi:10.5455/jcmr.2023.14.01.16



    Chicago Style

    Elisha, Ishaku L., Jurbe G. Gotep, Micah S. Makoshi, Joy G. Usman, Blessing Z. Shok, Kehinde F. Oyebade, Zainab Muhammad, Itodo E. Akogwu, Kpensalen B. Tondo, Hong Joseph, Edirin J. Akpojosevbe, Bitrus Yakubu, Maryam Muhammad Drug Development Division, National Veterinary Research Institute P.M.B. Vom, and Plateau Stat. "Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities." Journal of Complementary Medicine Research 14 (2023), 81-92. doi:10.5455/jcmr.2023.14.01.16



    MLA (The Modern Language Association) Style

    Elisha, Ishaku L., Jurbe G. Gotep, Micah S. Makoshi, Joy G. Usman, Blessing Z. Shok, Kehinde F. Oyebade, Zainab Muhammad, Itodo E. Akogwu, Kpensalen B. Tondo, Hong Joseph, Edirin J. Akpojosevbe, Bitrus Yakubu, Maryam Muhammad Drug Development Division, National Veterinary Research Institute P.M.B. Vom, and Plateau Stat. "Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities." Journal of Complementary Medicine Research 14.1 (2023), 81-92. Print. doi:10.5455/jcmr.2023.14.01.16



    APA (American Psychological Association) Style

    Elisha, I. L., Gotep, . J. G., Makoshi, . M. S., Usman, . J. G., Shok, . B. Z., , . K. F. O., Muhammad, . Z., Akogwu, . I. E., Tondo, . K. B., Joseph, . H., Akpojosevbe, . E. J., Yakubu, . B., Division, . M. M. D. D., & Stat, . P. (2023) Trends in Euphorbia hirta Research: A 30-year Bibliometric Appraisal of the Present Realities. Journal of Complementary Medicine Research, 14 (1), 81-92. doi:10.5455/jcmr.2023.14.01.16