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Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem

Godswill Nduka Anyasor, Funmilayo Onajobi, Odutola Osilesi, Olugbenga Adebawo, Efere M Oboutor.

Cited by (6)

Abstract
Aim: This study was designed to investigate the bioactive compounds in Costus afer Ker Gawl, an indigenous African medicinal plant whose leaf and stem extracts are used in the treatment of chronic inflammatory diseases especially rheumatism and arthritis.
Method: The bioactive compounds present in the n-butanol fractions of C. afer leaf and stem were identified using qualitative phytochemical evaluation and gas chromatographic-mass spectrometric (GC-MS) analytical method, comparing the mass spectra of the identified compounds with those of the National Institute of Standards and Technology (NIST) database library.
Results: Qualitative analysis detected alkaloids, saponins, diterpenes, triterpenes, phytosterol, phlobatannins and tannins in both n-butanol fractions of C. afer leaf and stem. Phenols were detected in leaves alone while flavonoids were present in stem alone. GC-MS data showed that the bioactive compounds in n-butanol fraction of C. afer leaf were indolizine, 2-methoxy-4vinylphenol, phytol, hexadecanoic acid- methyl ester, n-hexadecanoic acid, 9,12-octadecanoic acid-methyl ester, eicosane, cis-vaccenic acid and oleic acid while n-butanol fraction of C. afer stem containedbenzofuran,2,3-dihydro, 2-methoxy-4vinylphenol, 9-octadecenoic acid (Z)-2-hydroxy-1-(hydroxymethyl) ethyl ester, campesterol, stigmasterol, hexadecanoic acid-methyl ester, n-hexadecanoic acid and cis-vaccenic acid.
Conclusion: The bioactive compounds identified in the n-butanol fractions of C. afer leaves and stem may explain the folkloric use of C. afer plant in the treatment of chronic inflammatory and oxidative stress related diseases.

Key words: Costus afer; GC-MS; butanol; stem; leaf


 
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How to Cite this Article
Pubmed Style

Anyasor GN, Onajobi F, Osilesi O, Adebawo O, Oboutor EM. Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem. J Complement Med Res. 2014; 3(2): 78-84. doi:10.5455/jice.20140112010648


Web Style

Anyasor GN, Onajobi F, Osilesi O, Adebawo O, Oboutor EM. Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem. http://www.jocmr.com/?mno=49260 [Access: April 23, 2018]. doi:10.5455/jice.20140112010648


AMA (American Medical Association) Style

Anyasor GN, Onajobi F, Osilesi O, Adebawo O, Oboutor EM. Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem. J Complement Med Res. 2014; 3(2): 78-84. doi:10.5455/jice.20140112010648



Vancouver/ICMJE Style

Anyasor GN, Onajobi F, Osilesi O, Adebawo O, Oboutor EM. Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem. J Complement Med Res. (2014), [cited April 23, 2018]; 3(2): 78-84. doi:10.5455/jice.20140112010648



Harvard Style

Anyasor, G. N., Onajobi, F., Osilesi, O., Adebawo, O. & Oboutor, E. M. (2014) Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem. J Complement Med Res, 3 (2), 78-84. doi:10.5455/jice.20140112010648



Turabian Style

Anyasor, Godswill Nduka, Funmilayo Onajobi, Odutola Osilesi, Olugbenga Adebawo, and Efere M Oboutor. 2014. Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem. Journal of Complementary Medicine Research, 3 (2), 78-84. doi:10.5455/jice.20140112010648



Chicago Style

Anyasor, Godswill Nduka, Funmilayo Onajobi, Odutola Osilesi, Olugbenga Adebawo, and Efere M Oboutor. "Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem." Journal of Complementary Medicine Research 3 (2014), 78-84. doi:10.5455/jice.20140112010648



MLA (The Modern Language Association) Style

Anyasor, Godswill Nduka, Funmilayo Onajobi, Odutola Osilesi, Olugbenga Adebawo, and Efere M Oboutor. "Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem." Journal of Complementary Medicine Research 3.2 (2014), 78-84. Print. doi:10.5455/jice.20140112010648



APA (American Psychological Association) Style

Anyasor, G. N., Onajobi, F., Osilesi, O., Adebawo, O. & Oboutor, E. M. (2014) Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem. Journal of Complementary Medicine Research, 3 (2), 78-84. doi:10.5455/jice.20140112010648





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