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Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU.

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Abstract
Introduction: Indian spice contributes to food as both aroma and taste. Indian spices have been shown to treat diseases that range from colds, cough, and cancer. Ginger is a member of the Zingiberaceae genus, scientifically known as Zingiber officinale. It is the plant with medicinal and nutritional qualities that is the most essential.
Aim: The present study was conducted to evaluate the cytotoxic effect of ginger oleoresin against A549 lung cancer cell line.
Materials and Method: The Ginger oleoresin extract is collected from Synthetic Industries, with a product code - 4010000370. MTT assay was performed on the A549 cell line to assess the cytotoxic effect. The A549 cells are treated with different concentrations of ginger oleoresin (10, 20, 30, 50, 100 and 200 μg/ml) for 24 hrs and the cell viability was analysed using MTT assay.
Results: The results of MTT assay showed a dose dependent increase in cytotoxic effect of ginger oleoresin against A549 lung cancer cell line. The IC₅₀ value was 20 μg/ml for the extract.
Conclusion: The number of viable cells decreases as the drug concentration increases. Therefore, the present study concludes that ginger oleoresin possesses a strong cytotoxic effect. Hence, it is a promising candidate for anticancer therapy.

Key words: Cytotoxic effect; ginger; oleoresin; MTT assay; A549 cells, natural, innovation


 
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How to Cite this Article
Pubmed Style

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU. Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line. J Complement Med Res. 2021; 12(4): 1-6. doi:10.5455/jcmr.2021.12.04.01

Web Style

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU. Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line. https://www.jocmr.com/?mno=35951 [Access: April 25, 2022]. doi:10.5455/jcmr.2021.12.04.01

AMA (American Medical Association) Style

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU. Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line. J Complement Med Res. 2021; 12(4): 1-6. doi:10.5455/jcmr.2021.12.04.01


Vancouver/ICMJE Style

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU. Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line. J Complement Med Res. (2021), [cited April 25, 2022]; 12(4): 1-6. doi:10.5455/jcmr.2021.12.04.01


Harvard Style

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU (2021) Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line. J Complement Med Res, 12 (4), 1-6. doi:10.5455/jcmr.2021.12.04.01


Turabian Style

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU. 2021. Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line. Journal of Complementary Medicine Research, 12 (4), 1-6. doi:10.5455/jcmr.2021.12.04.01


Chicago Style

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU. "Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line." Journal of Complementary Medicine Research 12 (2021), 1-6. doi:10.5455/jcmr.2021.12.04.01


MLA (The Modern Language Association) Style

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU. "Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line." Journal of Complementary Medicine Research 12.4 (2021), 1-6. Print. doi:10.5455/jcmr.2021.12.04.01


APA (American Psychological Association) Style

RIESHY. V, ANITHA ROY, S. RAGHUNANDHAKUMAR, LAKSHMI THANGAVELU (2021) Cytotoxic Effect of Ginger Oleoresin Against Lung Cancer Cell Line. Journal of Complementary Medicine Research, 12 (4), 1-6. doi:10.5455/jcmr.2021.12.04.01


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