E-ISSN 2577-5669
 

Original Research 


Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus)

Thelma Ebele Ihedioha, Victor Nnaemeka Okechukwu, John Ikechukwu Ihedioha.

Abstract
AIM: This study investigated the effects of aqueous leaf infusion of Pterocarpus santalinoides DC on serum lipid profile (SLP) of guinea pigs (GPs).
METHODS: Fresh leaves of Pterocarpus. santalinoides were collected in February 2015. Aqueous leaf infusion was freshly prepared daily by soaking dried ground P. santalinoides leaf in hot water for 10 minutes. Twenty female GPs were randomly assigned into 4 groups (A – D) of 5 GPs each as follows: Group A – distilled water placebo per os (control), groups B, C and D – 1.5, 3.0 and 4.5 g/kg body weight (bw) of ground P. santalinoides leaf in 600ml of hot and cooled water per os respectively. Treatment was carried out for 28 days. Assay of SLP was done on days 0 (before treatment), and on days 14 and 28 of treatment following standard procedures.
RESULTS: The mean serum high density lipoprotein cholesterol (HDLC) of groups B, C and D rose to almost double its baseline values and was significantly (p < 0.05) higher than that of group A on day 28, while the mean serum low density lipoprotein cholesterol (LDLC) of group D was significantly lower (p<0.05) than those of other groups. The mean serum triglyceride and very low density lipoprotein cholesterol (VLDLC) of groups B and C were significantly lower (p < 0.05) than that of group A at day 14 and 28 of treatment.
CONCLUSION: The outcome of this study gives credence to the traditional use of this plant in the treatment of heart diseases.

Key words: Key words: Pterocarpus santalinoides, aqueous leaf infusion, serum lipid profile, guinea pigs.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Thelma Ebele Ihedioha
Articles by Victor Nnaemeka Okechukwu
Articles by John Ikechukwu Ihedioha
on Google
on Google Scholar
Article Statistics
 Viewed: 200
Downloaded: 51
Cited: 0

How to Cite this Article
Pubmed Style

Ihedioha TE, Okechukwu VN, Ihedioha JI. Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus). J Complement Med Res. 2018; 7(2): 154-160. doi:10.5455/jcmr.20180113015556


Web Style

Ihedioha TE, Okechukwu VN, Ihedioha JI. Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus). http://www.jocmr.com/?mno=284761 [Access: April 23, 2018]. doi:10.5455/jcmr.20180113015556


AMA (American Medical Association) Style

Ihedioha TE, Okechukwu VN, Ihedioha JI. Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus). J Complement Med Res. 2018; 7(2): 154-160. doi:10.5455/jcmr.20180113015556



Vancouver/ICMJE Style

Ihedioha TE, Okechukwu VN, Ihedioha JI. Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus). J Complement Med Res. (2018), [cited April 23, 2018]; 7(2): 154-160. doi:10.5455/jcmr.20180113015556



Harvard Style

Ihedioha, T. E., Okechukwu, V. N. & Ihedioha, J. I. (2018) Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus). J Complement Med Res, 7 (2), 154-160. doi:10.5455/jcmr.20180113015556



Turabian Style

Ihedioha, Thelma Ebele, Victor Nnaemeka Okechukwu, and John Ikechukwu Ihedioha. 2018. Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus). Journal of Complementary Medicine Research, 7 (2), 154-160. doi:10.5455/jcmr.20180113015556



Chicago Style

Ihedioha, Thelma Ebele, Victor Nnaemeka Okechukwu, and John Ikechukwu Ihedioha. "Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus)." Journal of Complementary Medicine Research 7 (2018), 154-160. doi:10.5455/jcmr.20180113015556



MLA (The Modern Language Association) Style

Ihedioha, Thelma Ebele, Victor Nnaemeka Okechukwu, and John Ikechukwu Ihedioha. "Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus)." Journal of Complementary Medicine Research 7.2 (2018), 154-160. Print. doi:10.5455/jcmr.20180113015556



APA (American Psychological Association) Style

Ihedioha, T. E., Okechukwu, V. N. & Ihedioha, J. I. (2018) Effects of aqueous leaf infusion of Pterocarpus santalinoides DC on the serum lipid profile of guinea pigs (Carvia porcellus). Journal of Complementary Medicine Research, 7 (2), 154-160. doi:10.5455/jcmr.20180113015556





Most Viewed Articles
  • Role of Cyperus rotundus oil in decreasing hair growth
    GHADA FAROUK ABD EL-KAREAM
    J Intercult Ethnopharmacol. 2012; 1(2): 111-118
    » Abstract & References » doi: 10.5455/jice.20120626100304

  • Ethno-dentistry: popular medicinal plants used for dental diseases in India
    Amit Bhardwaj, Shalu Verma Bhardwaj
    J Intercult Ethnopharmacol. 2012; 1(1): 62-65
    » Abstract & References » doi: 10.5455/jice.20120322035152

  • Total phenolic, flavonoids and tannin contents in different extracts of Artemisia absinthium
    Rajeev Singh, Pawan Kumar Verma, Gagandeep Singh
    J Intercult Ethnopharmacol. 2012; 1(2): 101-104
    » Abstract & References » doi: 10.5455/jice.20120525014326

  • Antimicrobial and phytochemical evaluation of the leaf, stem bark and root extracts of Cyathula prostrata (L) Blume against some human pathogens
    Gideon Ikechukwu Ogu, Williams Omotola Tanimowo, Perpetua Ugonna Nwachukwu, Bright Esegbuyota Igere
    J Intercult Ethnopharmacol. 2012; 1(1): 35-43
    » Abstract & References » doi: 10.5455/jice.20120407085952

  • Herbal Antibacterials: A Review
    Chirag Modi, Shailesh Mody, Hitesh Patel, Ghanshyam Dudhatra, Avinash Kumar, Madhavi Awale
    J Intercult Ethnopharmacol. 2012; 1(1): 52-61
    » Abstract & References » doi: 10.5455/jice.20120207113423

  • Preliminary phytochemical screening and evaluation of antibacterial activity of Dichrocepala integrifolia (L.f) O. kuntze
    Tesfaye Mohammed, Chalachew Teshale
    J Intercult Ethnopharmacol. 2012; 1(1): 30-34
    » Abstract & References » doi: 10.5455/jice.20120401054654

  • Medicinal plants with potential anti-arthritic activity:
    Manjusha Choudhary, Vipin Kumar, Hitesh Malhotra, Surender Singh
    J Intercult Ethnopharmacol. 2015; 4(2): 147-179
    » Abstract & References » doi: 10.5455/jice.20150313021918

  • Phytochemical and antibacterial activity of the extracts of Fagara zanthoxyloides on selected cariogenic and enteric bacterial isolates
    Martins Ajibade Adefisoye, Kwashie AjibadeAko-Nai, Mary Adejumoke Bisi-Johnson
    J Intercult Ethnopharmacol. 2012; 1(1): 1-6
    » Abstract & References » doi: 10.5455/jice.55-1333123486

  • Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits
    Kanwal Zahra, Muhammad Imran Sohail, Muhammad Anwar Malik
    J Intercult Ethnopharmacol. 2012; 1(1): 7-12
    » Abstract & References » doi: 10.5455/jice.20120403013109

  • Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants
    Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri
    J Intercult Ethnopharmacol. 2012; 1(1): 19-24
    » Abstract & References » doi: 10.5455/jice.20120227104636

  • Most Downloaded
  • Total phenolic, flavonoids and tannin contents in different extracts of Artemisia absinthium
    Rajeev Singh, Pawan Kumar Verma, Gagandeep Singh
    J Intercult Ethnopharmacol. 2012; 1(2): 101-104
    » Abstract & References » doi: 10.5455/jice.20120525014326

  • Herbal Antibacterials: A Review
    Chirag Modi, Shailesh Mody, Hitesh Patel, Ghanshyam Dudhatra, Avinash Kumar, Madhavi Awale
    J Intercult Ethnopharmacol. 2012; 1(1): 52-61
    » Abstract & References » doi: 10.5455/jice.20120207113423

  • Ethno-dentistry: popular medicinal plants used for dental diseases in India
    Amit Bhardwaj, Shalu Verma Bhardwaj
    J Intercult Ethnopharmacol. 2012; 1(1): 62-65
    » Abstract & References » doi: 10.5455/jice.20120322035152

  • Antimicrobial and phytochemical evaluation of the leaf, stem bark and root extracts of Cyathula prostrata (L) Blume against some human pathogens
    Gideon Ikechukwu Ogu, Williams Omotola Tanimowo, Perpetua Ugonna Nwachukwu, Bright Esegbuyota Igere
    J Intercult Ethnopharmacol. 2012; 1(1): 35-43
    » Abstract & References » doi: 10.5455/jice.20120407085952

  • Role of Cyperus rotundus oil in decreasing hair growth
    GHADA FAROUK ABD EL-KAREAM
    J Intercult Ethnopharmacol. 2012; 1(2): 111-118
    » Abstract & References » doi: 10.5455/jice.20120626100304

  • A review on ethnopharmacological potential of Aloe vera L.
    Md. Shamim Hossain, A.N.M Mamun-Or-Rashid, Nayeem Md. Towfique, Monokesh Kumer Sen
    J Intercult Ethnopharmacol. 2013; 2(2): 113-120
    » Abstract & References » doi: 10.5455/jice.20130612035300

  • Use of Aqueous Extract of Corn Silk in the Treatment of Urinary Tract Infection
    Ahmed Salih Sahib, Imad Hashim Mohammed, Saba Jasim Hamdan
    J Intercult Ethnopharmacol. 2012; 1(2): 93-96
    » Abstract & References » doi: 10.5455/jice.20120525123150

  • Preliminary phytochemical screening and evaluation of antibacterial activity of Dichrocepala integrifolia (L.f) O. kuntze
    Tesfaye Mohammed, Chalachew Teshale
    J Intercult Ethnopharmacol. 2012; 1(1): 30-34
    » Abstract & References » doi: 10.5455/jice.20120401054654

  • Phytochemical and antibacterial activity of the extracts of Fagara zanthoxyloides on selected cariogenic and enteric bacterial isolates
    Martins Ajibade Adefisoye, Kwashie AjibadeAko-Nai, Mary Adejumoke Bisi-Johnson
    J Intercult Ethnopharmacol. 2012; 1(1): 1-6
    » Abstract & References » doi: 10.5455/jice.55-1333123486

  • Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants
    Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri
    J Intercult Ethnopharmacol. 2012; 1(1): 19-24
    » Abstract & References » doi: 10.5455/jice.20120227104636

  • Most Cited Articles
  • Total phenolic, flavonoids and tannin contents in different extracts of Artemisia absinthium
    Rajeev Singh, Pawan Kumar Verma, Gagandeep Singh
    J Intercult Ethnopharmacol. 2012; 1(2): 101-104
    » Abstract & References » doi: 10.5455/jice.20120525014326
    Cited : 30 times [Click to see citing articles]

  • Guava leaves polyphenolics-rich extract inhibits vital enzymes implicated in gout and hypertension in vitro
    Emmanuel Anyachukwu Irondi, Samson Olalekan Agboola, Ganiyu Oboh, Aline Augusti Boligon, Margareth Linde Athayde, Francis O. Shode
    J Intercult Ethnopharmacol. 2016; 5(2): 122-130
    » Abstract & References » doi: 10.5455/jice.20160321115402
    Cited : 12 times [Click to see citing articles]

  • Antimicrobial and phytochemical evaluation of the leaf, stem bark and root extracts of Cyathula prostrata (L) Blume against some human pathogens
    Gideon Ikechukwu Ogu, Williams Omotola Tanimowo, Perpetua Ugonna Nwachukwu, Bright Esegbuyota Igere
    J Intercult Ethnopharmacol. 2012; 1(1): 35-43
    » Abstract & References » doi: 10.5455/jice.20120407085952
    Cited : 11 times [Click to see citing articles]

  • Some pharmacological effects of cinnamon and ginger herbs in obese diabetic rats
    Mostafa Abbas Shalaby, Hamed Yahya Saifan
    J Intercult Ethnopharmacol. 2014; 3(4): 144-149
    » Abstract & References » doi: 10.5455/jice.20140818050741
    Cited : 11 times [Click to see citing articles]

  • Potential antimalarials from African natural products: a review
    Bashir Lawal, Oluwatosin Kudirat Shittu, Adamu Yusuf Kabiru, Ali Audu Jigam, Maimuna Bello Umar, Eustace Bonghan Berinyuy, Blessing Uchenna Alozieuwa
    J Intercult Ethnopharmacol. 2015; 4(4): 318-343
    » Abstract & References » doi: 10.5455/jice.20150928102856
    Cited : 9 times [Click to see citing articles]

  • Analgesic, Anti-inflammatory and Antihyperlipidemic Activities of Commiphora molmol Extract (Myrrh)
    Mostafa Abbas Shalaby, Ashraf Abd-Elkhalik Hammouda
    J Intercult Ethnopharmacol. 2014; 3(2): 56-62
    » Abstract & References » doi: 10.5455/jice.20140130015014
    Cited : 9 times [Click to see citing articles]

  • Herbal medicine use among Turkish patients with chronic diseases
    Münevver Tulunay, Cenk Aypak, Hülya Yıkılkan, Süleyman Görpelioğlu
    J Intercult Ethnopharmacol. 2015; 4(3): 217-220
    » Abstract & References » doi: 10.5455/jice.20150623090040
    Cited : 7 times [Click to see citing articles]

  • Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy
    Luca Sorrentino, Salvatore Piraneo, Eliana Riggio, Silvia Basilicò, Alessandra Sartani, Daniela Bossi, Fabio Corsi
    J Intercult Ethnopharmacol. 2017; 6(1): 1-8
    » Abstract » doi: 10.5455/jice.20161229055245
    Cited : 7 times [Click to see citing articles]

  • Chemical constituents in n-butanol fractions of Costus afer ker Gawl leaf and stem
    Godswill Nduka Anyasor, Funmilayo Onajobi, Odutola Osilesi, Olugbenga Adebawo, Efere M Oboutor
    J Intercult Ethnopharmacol. 2014; 3(2): 78-84
    » Abstract & References » doi: 10.5455/jice.20140112010648
    Cited : 6 times [Click to see citing articles]

  • Evaluation of probiotic potential of yeasts isolated from traditional cheeses manufactured in Serbia and Croatia
    Milica Zivkovic, Neza Cadez, Ksenija Uroic, Marija Miljkovic, Maja Tolinacki, Petra Dousova, Blazenka Kos, Jagoda Suskovic, Peter Raspor, Ljubisa Topisirovic, Natasa Golic
    J Intercult Ethnopharmacol. 2015; 4(1): 12-18
    » Abstract & References » doi: 10.5455/jice.20141128051842
    Cited : 6 times [Click to see citing articles]