Role of Cyperus rotundus oil in decreasing hair growth

GHADA FAROUK ABD EL-KAREAM

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J Intercult Ethnopharmacol. 2012; 1(2): 111-118

doi: 10.5455/jice.20120626100304

Role of Cyperus rotundus oil in decreasing hair growth

GHADA FAROUK ABD EL-KAREAM.

Cited by (5)

Abstract
Background: There is a lack on the value of Egyptian Cyperus rotundus essential oil in the treatment of Androgenic hair.
Aim: To evaluate the efficacy and safety of application Egyptian Cyperus rotundus essential oil in comparison to 0.9% saline on androgenic hair.
Patients & Methods: Ninety one female patients with Androgenic hair (hirsutism and axillary hair) completed the study. They were randomly assigned to two groups: group I (active group) (n=47) and group II (control group) (n=44). Patients used topical Cyperus rotundus essential oil for six months and were evaluated at 6th month.
Results: The topical Cyperus rotundus oil was significantly more effective (p<0.05) than placebo with out side effects. This result was proved by three assessment methods; difference in hair count, independent observer assessment and patients’ self assessment.

Conclusion: The topical Egyptian Cyperus rotundus essential oil is an effective method in treating moderate degrees of hirsutism and axillary hair. But without affecting serum testosterone. This study is the first report on using Cyperus rotundus essential oil for decreasing hair growth.

Key words: Key words: Androgenic hair, Cyperus rotundus oil, Decrease hair growth, Hirsutism.

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REFERENCES

1. Deplewski D, Rosenfield RL. Role of hormones in pilosebaceous unit development. Endocr Rev 2000; 21:363-92. [DOI via Crossref]

2. Azziz R, Carmina E, Sawaya ME. Idiopathic hirsutism. Endocr Rev 2000; 21:347-62. [DOI via Crossref] [Pubmed]

3. Hatch R, Rosenfield RL, Kim MH, Tredway D. Hirsutism: implications, etiology, and management. Am J Obstet Gynecol 1981; 140:815-30.

4. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 1998;83: 3078-82. [DOI via Crossref] [Pubmed]

5. Rosenfield RL. Hirsutism and the variable response of the pilosebaceous unit to androgen. J Invest Dermatol (in press).

6. Reingold SB, Rosenfield RL. The relationship of mild hirsutism or acne in women to androgens. Arch Dermatol 1987; 123:209- 12. [DOI via Crossref]

7. Barnard L, Ferriday D, Guenther N, Strauss B, AH and Dye L. Quality of life and psychological well being in polycystic ovary syndrome. Hum. Reprod. 2007; 22 (8): 2279-2286.

8. TrÃ¼eb RM "Causes and management of hypertrichosis". American journal of clinical dermatology 2002; 3 (9): 617â€“27. [DOI via Crossref]

9. Quinones J, Viddy L, Bouchardeau C. "Hypertrichosis - Real Life Werewolves?" ABC News. Retrieved September 20, 2009.

10. Bryan PW. The Papyrus Ebers. Geoffrey Bles: London, 1930

11. Rho S S, Park SJ, Hwang SL, Lee HM, Kim CD, Lee IH. The hair growth promoting effect of Asia sari radix extract and its molecular regulation. "Journal of Dermatological Science", 2005; 38(2), 89 â€“ 97.

12. Roy RK, Thakur M, Dixit VK. Hair growth promoting activity of Eclipta alba Hassk. In albino rats. "Indian drugs", 2006; 43 (12), 951-956.

13. Lee CH, Hwang DS, Kim HG, Oh H, Park H, Cho JH, et al. Protective effect of Cyperi rhizoma against 6-hydroxydopamine-induced neuronal damage. J Med Food. 2010; 13(3):564-71. [DOI via Crossref] [Pubmed]

14. Nishikant AR, Naresh JN. Antidiabetic activity of hydro-ethanolic extract of Cyperus rotundus in alloxan induced diabetes in rats. "Journal of Fitoterpia" 2006; 77, 585-588.

15. Yazdanparast R, Ardestani A. In vitro antioxidant and free radical scavenging activity of Cyperus rotundus. J Med Food. 2007; 10(4):667-74. [DOI via Crossref] [Pubmed]

16. Kilani-Jaziri S, Neffati A, Limem I, Boubaker J, Skandrani I, Sghair MB, Bouhlel I, Bhouri W, Mariotte AM, Ghedira K, Dijoux Franca MG, Chekir-Ghedira L. Relationship correlation of antioxidant and antiproliferative capacity of Cyperus rotundus products towards K562 erythroleukemia cells. Chem Biol Interact. 2009; 181(1):85-94. [DOI via Crossref] [Pubmed]

17. Evans BA, Griffiths K, Morton MS. Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids. J Endocrinol. 1995; 147(2):295-302. [DOI via Crossref] [Pubmed]

18. Duarte MC, Figueira GM, Sartoratto A, Rehder VL & Delarmelina C. Anti-Candida activity of Brazilian medicinal plants. J Ethnopharmacol. 2005;97(2):305-11. Epub 2005 Jan 5.

19. Tambekar DH, Khante BS, Chandak BR, Titare AS, Boralkar SS, Aghadte SN. Screening of Antibacterial Potentials of Some Medicinal Plants from Melghat Forest in India. Afr J Tradit Complement Altern Med. 2009; 6(3): 228â€“232.

20. Kumar V. Prashanth, Chauhan Neelam S., Padh Harish, Rajani M. Search for antibacterial and antifungal agents from selected Indian medicinal plants. "Journal of Ethnopharmacology", 2006; 107 & 182â€“188.

21. Sarbhoy AK, Varshney JL, Naturwiss ZB. Efficacy of some essential oils and their constituents on few ubiquitous molds. 1978; 133 (7-8):723-5.

22. Seo EJ, Lee DU, Kwak JH, Lee SM, Kim YS, Jung YS. Antiplatelet effects of Cyperus rotundus and its component (+)-nootkatone. J Ethnopharmacol. 2011;135(1):48-54. [DOI via Crossref] [Pubmed]

23. Dang GK, Parekar RR, Kamat SK, Scindia AM, Rege NN. Antiinflammatory activity of Phyllanthus emblica, Plumbago zeylanica and Cyperus rotundus in acute models of inflammation. Phytother Res. 2011;25(6):904-8. [DOI via Crossref] [Pubmed]

24. Sahib AS, Sloo SA, Khidir A. Role of Mentha longifolia and Cyperus rotundus in the treatment of irritable bowel syndrome. Journal of Medical and Pharmaceutical Sciences 2011, 1(3): 08-16

25. Ohira S, Hasegawa T, Hyashi KI, Hoshino T, Takaoka D, Nozaki H. Sesquiterpenoids from Cyperus rotundus. Phytochemistry 1998; 47: 1577â€“1581. [DOI via Crossref]

26. Kilani S, Abdelwahed A, Chraief I, Ben Ammar R, Hayder N, Hammami M,Ghedira K, Chekir-Ghedira L. Chemical composition, antibacterial and antimutagenic activities of essential oil from (Tunisian) Cyperus rotundus. J.Essent. Oil Res 2005; 17: 695â€“700. [DOI via Crossref]

27. Joulain D, Konig WA. The Atlas of Spectral Data of Sesquiterpene Hydrocarbons. E. B.-Verlag, Hamburg 1998.

28. Hikino H, Ito K, Aota K. Structure and absolute configuration of cyperotundone. Chemical and Pharmaceutical Bulletin 1966; 14: 890â€“899. [DOI via Crossref] [Pubmed]

29. Nyasse B, Ghogumu Tih R, Sodengam BL, Martin MT, Bodo B. Mandassidione and other sesquiterpenic ketones from Cyperus articulatus. Phytochemistry 1988; 27: 3319â€“3321. [DOI via Crossref]

30. Hikino H, Takemoto T. Structure and absolute configuration of cyperol and isocyperol. Chemical and Pharmaceutical Bulletin 1967; 1929â€“1933.

31. Howe R, Mc Quillin FJ. The structure of cyperone. Part IV. The synthesis of natural (+)-a-cyperone, its enantiomorphism and epimer. Journal of the Chemical Society 1955; 2423â€“2428.

32. Haaksma AA, Jansen BJM, de Groot A. Lewis acid catalyzed Diels-Alder reactions of S-(+)-carvone with silyloxy dienes. Total synthesis of (+)-a-cyperone. Tetrahedron 1992; 48: 3121â€“3130. [DOI via Crossref]

33. "Egyptian Pharmacopoeia" General Organization for Governmental Printing Office, 31, (1984).

34. Tang X, Zhu X, Liu S, Nicholson RC, Ni X. Phytoestrogens induce differential estrogen receptor beta-mediated responses in transfected MG-63 cells. Endocrine. 2008 Oct 21.

35. Yu H, Xu LX. Separation and determination of flavonols in the flowers of Carthamus tinctorius by RP-HPLC. 1997; 32(2):120-2.

36. Alijanpoor R, Bejehmir AP, Mokmeli S. Successful white hair removal with combined coloring and intense pulsed Light (IPL): a randomized clinical trial. Photomed Laser Surg. 2011; 29(11):773-9. [DOI via Crossref] [Pubmed]

37. Sand M, Bechara FG, Sand D, Altmeyer P, Hoffmann K. A randomized, controlled, double-blind study evaluating melanin-encapsulated liposomes as a chromophore for laser hair removal of blond, white, and gray hair. Ann Plast Surg. 2007; 58(5):551-4. [DOI via Crossref] [Pubmed]

38. Shapiro J, Lui H. Treatments for unwanted facial hair. Skin Therapy Lett. 2005; 10(10):1-4.

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How to Cite this Article

Pubmed Style

GHADA FAROUK ABD EL-KAREAM. Role of Cyperus rotundus oil in decreasing hair growth. J Complement Med Res. 2012; 1(2): 111-118. doi:10.5455/jice.20120626100304

Web Style

GHADA FAROUK ABD EL-KAREAM. Role of Cyperus rotundus oil in decreasing hair growth. http://www.jocmr.com/?mno=20795 [Access: June 18, 2019]. doi:10.5455/jice.20120626100304

AMA (American Medical Association) Style

GHADA FAROUK ABD EL-KAREAM. Role of Cyperus rotundus oil in decreasing hair growth. J Complement Med Res. 2012; 1(2): 111-118. doi:10.5455/jice.20120626100304

Vancouver/ICMJE Style

GHADA FAROUK ABD EL-KAREAM. Role of Cyperus rotundus oil in decreasing hair growth. J Complement Med Res. (2012), [cited June 18, 2019]; 1(2): 111-118. doi:10.5455/jice.20120626100304

Harvard Style

GHADA FAROUK ABD EL-KAREAM (2012) Role of Cyperus rotundus oil in decreasing hair growth. J Complement Med Res, 1 (2), 111-118. doi:10.5455/jice.20120626100304

Turabian Style

GHADA FAROUK ABD EL-KAREAM. 2012. Role of Cyperus rotundus oil in decreasing hair growth. Journal of Complementary Medicine Research, 1 (2), 111-118. doi:10.5455/jice.20120626100304

Chicago Style

GHADA FAROUK ABD EL-KAREAM. "Role of Cyperus rotundus oil in decreasing hair growth." Journal of Complementary Medicine Research 1 (2012), 111-118. doi:10.5455/jice.20120626100304

MLA (The Modern Language Association) Style

GHADA FAROUK ABD EL-KAREAM. "Role of Cyperus rotundus oil in decreasing hair growth." Journal of Complementary Medicine Research 1.2 (2012), 111-118. Print. doi:10.5455/jice.20120626100304

APA (American Psychological Association) Style

GHADA FAROUK ABD EL-KAREAM (2012) Role of Cyperus rotundus oil in decreasing hair growth. Journal of Complementary Medicine Research, 1 (2), 111-118. doi:10.5455/jice.20120626100304

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